Automated 3D (SonoAVC) vs 2D Ovarian Follicles Assessment in IVF Cycles: a Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 54
- 试验地点
- 2
- 主要终点
- percentage of matured oocytes
研究概览
简要总结
Accurate assessment of the size of follicles is important in IVF treatment.Timing of oocyte maturation and subsequent egg collection is largely based on follicle size. An accurate assessment of follicle size and appropriate timing of HCG result in retrieval of more mature oocytes, improved fertilization and higher pregnancy rates. in 3D technology- fter the capturing of a 3D image of an ovary, SonoAVC automatically analyzes the volume dataset, identifies the boundaries of hypoechoic follicles, and provides estimates of their absolute dimensions. These measurements include the largest diameters in three orthogonal planes, the mean follicular diameter (MFD), the volume of the follicle, and the volume-based diameter (d(V)) of the follicle. In the current study the investigators aim to evaluate the use of this automated technique of follicle measurement vs. standard 2D technology on the timing of oocyte maturation and subsequent oocyte retrieval. The investigators speculate that 3D assessment will increase the rate of mature oocyte collection, and eventually will improve other treatment outcomes such as fertilization rate.
详细描述
Not desired
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 39 Years(Adult)
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Age:18-39, cycle number 1-4
排除标准
- •Endometriosis
- •Poor ovarian response
- •TESA sperm
结局指标
主要结局
percentage of matured oocytes
时间窗: one IVF cycle (within two weeks)
次要结局
- Fertilization rate in ICSI(one IVF cycle/ patient (within two weeks))
研究者
avi ben haroush
Head of Fertility Preservation Service,IVF and Infertility Unit
Rabin Medical Center
