Automated Folliculometry Using Five-Dimensional Ultrasound
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Automated Folliculometry Using Five-Dimensional Ultrasound
- Sponsor
- Ain Shams University
- Enrollment
- 67
- Primary Endpoint
- The Mean Follicular Diameter by Two-Dimensional Ultrasound
- Status
- Completed
- Last Updated
- 8 years ago
Overview
Brief Summary
The aim of the study to evaluate Five-Dimensional Ultrasound in automated measurement of ovarian follicles with controlled ovarian stimulation in contrast to the conventional 2D ultrasound
Detailed Description
This is a Prospective pilot study that will be performed at the Fetal Care Unit at Ain Shams University Maternity Hospital. 72 women will be recruited from the the Fetal Care Unit who will fulfill the inclusion criteria. They will be counseled to be included into the study. All cases will be subjected to: full history taking including patient's age, parity,last menstrual period , past history of medical disorders, clinical examinations (General and abdominal). Two-Dimensional Ultrasound and Five-Dimensional Ultrasound will be done for all cases for assessment of ovarian follicles after controlled ovarian stimulation by clomid 50 mg5×2×1 The automated software allows for automated three-dimensional follicular measurement.The software then analyzes the volume and automatically identifies all of the follicles in the ovary. The software also automatically generates several volumetric parameters of each and every identified follicle.
Investigators
Rehab Mohamed Abdelrahman
Principal Investigator
Ain Shams University
Eligibility Criteria
Inclusion Criteria
- •all women between 25 to 35 years of age
- •all women have a normal body mass index(18-25kg/M\^2)
- •regular menstrual cycles
- •all women would be receiving ovarian stimulation using clomiphene citrate (clomid 50 mg) for ≥5 days starting from 5th day of the cycle then they will be scanned by the same physician using Two Dimensional Ultrasound then Five Dimensional Ultrasound U/S
Exclusion Criteria
- •medical disorders
- •obesity. BMI\>30
Outcomes
Primary Outcomes
The Mean Follicular Diameter by Two-Dimensional Ultrasound
Time Frame: 10th day of the menstrual cycle
All women would be receiving ovarian stimulation using clomiphene citrate (clomid 50 mg) once daily for 5 days starting from 2nd day of the cycle then they will be scanned at 10th day by the same physician using Two Dimensional Ultrasound was done. Each follicle was assessed by measuring the maximal diameters on three orthogonal planes. The mean of three diameters was calculated.
Secondary Outcomes
- The Volume-based Diameter (dV) of the Follicle by Five-Dimensional Ultrasound(10th day of the menstrual cycle)
- The Mean Follicular Diameter by Five-Dimensional Ultrasound(10th day of the menstrual cycle)