Accelerating Colorectal Cancer Screening Through Implementation Science in Appalachia

Not Applicable

Completed

• Conditions: Colorectal Cancer
• Interventions: Behavioral: Multi-level intervention to increase CRC screening

• Registration Number: NCT04427527
• Lead Sponsor: University of Kentucky

Brief Summary

This project aims to implement a multi-level group randomized trial, delayed intervention that includes components targeting clinics, providers, patients, and the community to increase colorectal cancer (CRC) screening, follow-up, and referral-to-care among patients age 50-74 in 12 counties in Appalachian Kentucky and Ohio. The 12 counties will be assigned to one of two study groups (early vs. delayed) and outcome measures (rate of CRC screening) will be obtained from clinic-level electronic health record data and a county-level behavioral assessment telephone survey. The hypothesis for the project is that the multi-level intervention will increase the clinic and county level CRC screening rates.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2020-06-03
• Study First Submitted QC: 2020-06-08
• Study First Posted: 2020-06-11
• Study Start: 2020-08-19
• Primary Completion: 2025-03-31
• Study Completion: 2025-03-31
• Status Verified: 2025-04
• Last Update Submitted: 2025-04-04
• Last Update Posted: 2025-04-06

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 5413

Inclusion Criteria

• age 50-74
• all races, sexes and genders
• resident of the study area

Exclusion Criteria

.no exclusions based on gender, race or ethnicity

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: FACTORIAL

Arm && Interventions

Group	Intervention	Description
Multi-level Intervention	Multi-level intervention to increase CRC screening	Receives the project intervention first

Primary Outcome Measures

Name	Time	Method
CRC screening - clinic level	12 months	Change in clinic-level screening rate from baseline to the end of the 12-month active intervention period, assessed through clinic electronic health record data

Secondary Outcome Measures

Name	Time	Method
CRC screening - community level	12 months	Self-reported participation in CRC screening from baseline to the end of the 12-month active intervention period, assessed through telephone surveys

Trial Locations

Locations (2)

Markey Cancer Center; 🇺🇸 Lexington, Kentucky, United States

Ohio State University; 🇺🇸 Columbus, Ohio, United States