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临床试验/ACTRN12613001321730
ACTRN12613001321730进行中(未招募)2 期

Prospective non randomized pilot study using Sirolimus and Prednisone to induce remission in patients with Erdheim-Chester Disease.

niversity of Parma, Department of Clinical and Experiment Medicine0 个研究点目标入组 10 人开始时间: 2013年11月28日最近更新:

试验速览

阶段
2 期
状态
进行中(未招募)
发起方
入组人数
10

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional
分配方式
Non-randomised trial
主要目的
Treatment
盲法
Open (masking not used)

入排标准

年龄范围
18 Years 至 75 Years(—)
性别
All

入选标准

  • Diagnosis of Erdheim-Chester with systemic involvement
  • - Active disease (newly diagnosed progressive disease in patients undergoing other treatments)

排除标准

  • - Concurrent active malignancies or serious infections
  • - Hypersensitivity to sirolimus and/or prednisone and/or contraindications to their use (uncontrolled diabetes
  • mellitus, severe osteoporosis with previous fractures)
  • - Proteinuria > 1g/24h
  • - Recent major surgery and/or post-surgical complications
  • - Pregnancy
  • - Patients partecipating in other trials

研究者

发起方
niversity of Parma, Department of Clinical and Experiment Medicine

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