MedPath

Safety and Pharmacokinetic Study of YKP3089 as Adjunctive Therapy in Subjects With Partial Onset Seizures

Phase 3
Completed
Conditions
Partial Epilepsy
Interventions
Registration Number
NCT02535091
Lead Sponsor
SK Life Science, Inc.
Brief Summary

This is a multicenter, open label study to assess the safety and pharmacokinetics of YKP3089 as adjunctive therapy in subjects with partial onset seizures. Initially, subjects taking phenytoin or phenobarbital will be enrolled followed by additional subjects taking anti-epileptic drugs (AED) other than phenytoin and phenobarbital to further investigate long-term safety.

Detailed Description

see above

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
1345
Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
YKP3089YKP3089Multiple dose
Primary Outcome Measures
NameTimeMethod
Summary of Treatment-Emergent Adverse Events (TEAEs)1 day to up to 215 weeks after first dose.

TEAEs were defined as Adverse events (AEs) with onset on or after the start of study medication, up to last dose date of study medication + 14 days or onset before study medication and worsened after starting study medication, up to last dose date of study medication + 14 days.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (121)

Xen Institute

🇺🇸

Phoenix, Arizona, United States

Banner-University Medical Center Phoenix

🇺🇸

Phoenix, Arizona, United States

Arkansas Epilepsy Program

🇺🇸

Little Rock, Arkansas, United States

Kaiser Permanente - Southern California Medical Group

🇺🇸

Anaheim, California, United States

Neuro Pain Medical Center

🇺🇸

Fresno, California, United States

California Pacific Medical Center

🇺🇸

San Francisco, California, United States

Blue Sky Neurology

🇺🇸

Englewood, Colorado, United States

Bradenton Research Center Inc

🇺🇸

Bradenton, Florida, United States

NW FL Neurology Center

🇺🇸

Gulf Breeze, Florida, United States

Emory Brain Health Center

🇺🇸

Atlanta, Georgia, United States

Scroll for more (111 remaining)
Xen Institute
🇺🇸Phoenix, Arizona, United States

MedPath

Empowering clinical research with data-driven insights and AI-powered tools.

© 2025 MedPath, Inc. All rights reserved.