The Investigation of a Fluorescence/Elastic Scattering Spectroscopy (F-ESS) Device for Oral Tissue Characterization
- Conditions
- Other Lesions of Oral Mucosa
- Interventions
- Device: Fluorescence/Elastic Scattering Spectroscopy
- Registration Number
- NCT00764569
- Lead Sponsor
- University of California, Irvine
- Brief Summary
The overall objective of this work is to identify changes in the optical properties of oral tissues to develop a non-invasive tool for the detection, diagnosis and screening of oral pathology so that treatment can be provided at the earliest possible time.
- Detailed Description
Specifically, we will be obtaining optical spectroscopic data using a fiber optic contact probe that exploits elastic-scattering spectroscopy and fluorescence spectroscopy. Both of these technique have independently shown to provide signatures for the onset of cancer, with varied success. The purpose of this effort is to combine the two techniques and develop and understanding of the signatures obtained in both normal and abnormal oral tissue with simultaneous collection of these optical signatures.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 77
- adult over 18 years of age
- younger than 18 years of age
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Oral Tissue measurement Fluorescence/Elastic Scattering Spectroscopy Fluorescence/Elastic Scattering Spectroscopy Oral tissue measurement
- Primary Outcome Measures
Name Time Method Diagnostic Tool 4 weeks Fluorescence/Elastic Scattering Spectroscopy Oral tissue measurement
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (2)
Beckman Laser Institute Medical clinic
🇺🇸Irvine, California, United States
UCI student health center
🇺🇸Irvine, California, United States