a Non-invasive Device for the Detection, Diagnosis and Screening of Oral Pathology
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Other Lesions of Oral Mucosa
- Sponsor
- University of California, Irvine
- Enrollment
- 77
- Locations
- 2
- Primary Endpoint
- Diagnostic Tool
- Status
- Completed
- Last Updated
- 3 years ago
Overview
Brief Summary
The overall objective of this work is to identify changes in the optical properties of oral tissues to develop a non-invasive tool for the detection, diagnosis and screening of oral pathology so that treatment can be provided at the earliest possible time.
Detailed Description
Specifically, we will be obtaining optical spectroscopic data using a fiber optic contact probe that exploits elastic-scattering spectroscopy and fluorescence spectroscopy. Both of these technique have independently shown to provide signatures for the onset of cancer, with varied success. The purpose of this effort is to combine the two techniques and develop and understanding of the signatures obtained in both normal and abnormal oral tissue with simultaneous collection of these optical signatures.
Investigators
Beckman Laser Institute and Medical Center
Petra Wilder-Smith, DDS., PhD., Professor, Director of Dentistry
University of California, Irvine
Eligibility Criteria
Inclusion Criteria
- •adult over 18 years of age
Exclusion Criteria
- •younger than 18 years of age
Outcomes
Primary Outcomes
Diagnostic Tool
Time Frame: 4 weeks
Fluorescence/Elastic Scattering Spectroscopy Oral tissue measurement