Efficacy of Prescription Methods for High-intensity Interval Training in Patients Enrolled in Outpatient Cardiac Rehabilitation
概览
- 阶段
- 不适用
- 干预措施
- Constant High Intensity Interval Training (CON-HIIT)
- 疾病 / 适应症
- Cardiac Rehabilitation
- 发起方
- Mayo Clinic
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Change in cardiorepiratory fitness
- 状态
- 进行中（未招募）
- 最后更新
- 3个月前
概览
简要总结
The purpose of the study is to examine the effect of two different high intensity interval training (HIIT) prescription approaches on improving fitness, heart function, and the ability of the body's muscles to receive oxygen.
研究者
入排标准
入选标准
- •Adult 18 years and older.
- •English speaking.
- •Able to provide consent.
- •Has a qualifying indication for center-based cardiac rehabilitation that is non-surgical (i.e., Acute coronary syndrome, myocardial infarction, percutaneous coronary intervention, and stable angina).
排除标准
- •Participants referred to cardiac rehabilitation following coronary artery bypass surgery, heart valve repair/replacement, heart transplant, or those with ventricular assist devices.
- •Patients who are unable to engage in a regularly structured exercise training program as part of a clinically indicated center-based outpatient cardiac rehabilitation program are not eligible.
- •Patients unable/unwilling to provide informed consent will not be enrolled.
- •Patients identified as having a contraindication to high intensity exercise.
研究组 & 干预措施
Standard-care interval-training group
Subjects will complete a standard interval-training program that remains constant for the entire 12 weeks of cardiac rehabilitation.
干预措施: Constant High Intensity Interval Training (CON-HIIT)
Progressive interval-training group
Subjects will complete an interval-training program during which the number of intervals and the duration of each interval are changed across the 12-week cardiac rehabilitation program.
干预措施: Progressive High Intensity Interval Training (PRO-HIIT)
结局指标
主要结局
Change in cardiorepiratory fitness
时间窗: Pre and post study completion, approximately 12 weeks
Measure as peak oxygen consumption (VO2 peak)
次要结局
- Change in blood pressure(Pre and post study completion, 12 weeks)
- Changes in mechanoreflex stimulation and sensitization(Pre and post study completion, 12 weeks)
- Change in locomotor muscle oxygenation(Pre and post study completion, 12 weeks)
- Change in cardiac function(Pre and post study completion, 12 weeks)
- Change in blood lipids(Pre and post study completion, 12 weeks)
- Change in oxygen uptake response time(Weekly, over 12 weeks)
- Change in metaboreflex stimulation(Pre and post study completion, 12 weeks)
- Change in body composition(Pre and post study completion, 12 weeks)
- Change in physical activity(Pre and post study completion, 12 weeks)