Elite Sport and Development of Asthma
- Registration Number
- NCT00262587
- Lead Sponsor
- Bispebjerg Hospital
- Brief Summary
International studies have shown that elite athletes have a high prevalence of respiratory symptoms and asthma as compared to normal subjects. It is unclear whether the increased prevalence of asthma in elite athletes reflects "traditional asthma" or whether it is a special form of "sports asthma". The treatment of elite athletes with asthma seems to vary widely, and only a few studies have focused on the treatment of elite athletes with asthma. Further knowledge of the pathogenesis of sports asthma would lead to a greater understanding and better treatment of the condition. This study will investigate the type of airway inflammation in elite athletes and examine the effect of treatment with inhaled steroids in combination with long-acting beta-agonists versus placebo in the same group.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 18
- Elite athletes
- Informed consent
- Doctor diagnosed asthma
- Current smoker or more than 10 pack-years
- Pregnancy, breast feeding or planning pregnancy during the study.
- ICS within the last 4 weeks prior to visit 1.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Placebo Placebo Placebo inhaler (sugar powder) Seretide Seretide Seretide inhaler
- Primary Outcome Measures
Name Time Method Eucapnic voluntary hyperventilation (EVH) End of study Exhaled Nitric Oxide End of study
- Secondary Outcome Measures
Name Time Method Respiratory symptoms End of study Lung function End of study
Trial Locations
- Locations (1)
Respiratory and Allergy Research Unit, Department of Respiratory Medicine, Bispebjerg Hospital
🇩🇰Copenhagen, Denmark