Airway Responsiveness and Inflammation in Adolescent Elite Swimmers: a 3-Year Prospective Follow-up Study
- Conditions
- Asthma
- Registration Number
- NCT00841425
- Lead Sponsor
- Bispebjerg Hospital
- Brief Summary
Previously the investigators have found that adolescent elite swimmers, who have been involved in competitive swimming for only a few years, have not developed respiratory symptoms, signs of airway inflammation or airway hyperresponsiveness exept for a slight increase in airway responsiveness to eucapnic voluntary hyperpnea. In the current study, the investigators will be doing a 3-year follow-up study on the swimmers studied previously.
- Detailed Description
Even though studies suggest that elite sport can cause AHR and airway inflammation, more studies are needed to elucidate how and when AHR and airway inflammation develop; and there is a lack of follow-up studies. The present study will give us a chance to do a follow-up study to register changes in AHR and airway inflammation in athletes without any significant airway changes at baseline.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 33
- Age 15-19 years
- Part of the Danish National Swimming Association's talent program for young swimmers at the baseline study
- Informed consent
- Upper respiratory tract infection in the previous 4 weeks (visits will be postponed)
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Airway responsiveness to eucapnic voluntary hyperpnea and methacholine Three years
- Secondary Outcome Measures
Name Time Method Airway inflammation Three years
Trial Locations
- Locations (1)
Respiratory and Allergy Research Unit, Department of Respiratory Medicine L, Bispebjerg Hospital
🇩🇰Copenhagen, Denmark