Screening of Patients With Rheumatoid Arthritis for Interstitial Lung Disease With Radiographic and Labor Methods
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 500
- 试验地点
- 3
- 主要终点
- pattern of ILD
研究概览
简要总结
The quantitative and qualitative analysis of RA lung involvement in the Hungarian population
详细描述
Interstitial lung disease (ILD) accounts for a significant proportion of mortality and morbidity in rheumatoid arthritis (RA). The aim of this prospective longitudinal study is to asess the interstitial lung involvement in Hungarian rheumatoid arthritis patients. Laboratory markers, X-ray based imaging methods, pulmonological functional tests, QOL questionnaire and sleep quality assessement questionnaire are used to estimate the interstitial lung disease. Also smaller cross-sectional studies about the imaging parameters and a national register is planned to be created based on these data.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 40 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •diagnosis of RA
排除标准
- •pregnancy, breastfeeding
- •previous diagnosis of ILD, lung cancer, registered lung infection in the last 2 months
结局指标
主要结局
pattern of ILD
时间窗: From baseline to at least 5 years
to characterize the ILD patterns based on imaging methods
Prevalence of ILD
时间窗: From baseline to at least 5 years
detection of ILD with imaging methods
次要结局
- Correlation with biomarkers(From baseline to at least 2 years)
研究者
dr.Kinga Fritsch
MD
Polyclinic of the Hospitaller Brothers of St. John of God, Budapest