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Clinical Trials/NCT05593835
NCT05593835
Not yet recruiting
Not Applicable

Protocol for a Cluster Randomised Trial of a Goal-Oriented Care Approach for Multimorbidity Patients Supported by a Digital Platform

Universidade Nova de Lisboa0 sites1,380 target enrollmentJune 1, 2025
ConditionsChronic Disease

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Chronic Disease
Sponsor
Universidade Nova de Lisboa
Enrollment
1380
Primary Endpoint
Health related quality of life
Status
Not yet recruiting
Last Updated
2 years ago

Overview

Brief Summary

This study aims to assess whether the use of the METHIS digital platform using a patient-centered approach contributes to an improvement in the quality of life, mental health and physical activity of patients with multimorbidity followed up in Primary Health Care. Practices will be randomly allocated between: providing access to consultations through the METHIS platform (intervention) or following patients by the traditional method (control). They will complete questionnaires on quality of life, mental health and report the number of steps taken, at the beginning and end of the study.

Detailed Description

A superiority, cluster randomised trial will be conducted at Primary Health Care Practices (1:1 allocation ratio). All public practices in the Lisbon and Tagus Valley Region, Portugal, not involved in a previous pilot trial, will be eligible. The intervention combines a training programme and a customised Information System (METHIS). Both are designed to help clinicians to adopt a Goal-Oriented Care Model approach and to encourage patients and carers to play a more active role in autonomous healthcare.

Registry
clinicaltrials.gov
Start Date
June 1, 2025
End Date
May 31, 2027
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • community-dwelling people
  • aged 50 or older
  • with complex multimorbidity (co-occurrence of three or more chronic conditions affecting three or more different body systems)
  • with access to an Internet connection and a communication technology device

Exclusion Criteria

  • inability to: provide informed consent, to read or write, inability to access an email or electronic device, even when helped by an informal caregiver

Outcomes

Primary Outcomes

Health related quality of life

Time Frame: Participants will be asked to fill in the SF-12 questionnaire at baseline and at 12 months.

Participants will be asked to fill in the SF-12 questionnaire which generates a physical component score (PCS) and a mental component score (MCS). The primary outcome will be the mean difference in the variation (delta) of the PCS of SF-12 between baseline and 12 months. The SF-12 can be filled in 2-4 minutes, and it is validated for the Portuguese population. Minimum important differences validated across large populations and multiple disease categories are a change in between 2 and 3 points from the population mean of 50.

Secondary Outcomes

  • Physical activity(Participants will wear the SmartBand for 12 months.)
  • Number of serious adverse events (clinician-reported)(Family physicians will be asked, at 6 and 12 months after randomization, to check the life status of enrolled patients and whether patients in the trial were admitted to a hospital or had a visit to an emergency service since the randomization date.)
  • Mental health status(Participants will complete the HADS-A and HADS-D questionnaire at baseline and at 12 months.)
  • Number of potentially missed diagnoses (clinician-reported)(Potentially missed diagnoses will be reported 6 months after the intervention phase. In this way a compromise between avoiding recall bias and allowing enough time for a missed diagnosis to become clinically apparent is achieved.)

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