To find relationship between oxygen level and death after surgery in cancer patients.

Completed

• Conditions: Medical and Surgical,

• Registration Number: CTRI/2023/05/052669
• Lead Sponsor: Dr Sarthak Misra

Brief Summary

The peripheral perfusion index (PPI), derived from the photoelectric plethysmography pulse oximetry signal, decreases in response to hypoperfusion reflecting the ratio between the pulsatile and non-pulsatile component of the arterial waveform in the tissue. Thus, changes in peripheral perfusion, both from reduced Cardiac Output and sympathetically mediated peripheral vasoconstriction to augment central blood volume, are reflected in PPI. Reduced peripheral perfusion has been associated with both morbidity and mortality in critically ill patients, patients with septic shock, and after acute or major elective surgery.

Detailed Description

Not available

Study Timeline

• Study Start: 2023-05-25
• Last Update Posted: 2024-12-20
• Study Completion: 2025-01-20

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 122

Inclusion Criteria

• 1.Patients willing to participate.
• 2.Patients > 18 years of age.
• 3.Patients with no limb deformities.
• 4.ASA grade 1-4 patients.
• 5.Operative procedure requiring General Anaesthesia.

Exclusion Criteria

• 1.Patients refusal to participate.
• 2.Patients age <18 years of age.
• 3.Any contraindications to General Anaesthesia.
• 4.Patients with limb deformities, amputated limbs, gangrene, PVD.
• 5.ASA grade 5 and above.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To evaluate the association between perioperative PPI with postoperative morbidity and mortality after first 36 hours of stay in ICU.	To evaluate the association between perioperative PPI with postoperative morbidity and mortality after first 36 hours of stay in ICU.

Secondary Outcome Measures

Name	Time	Method
1.Inra operative hemodynamics(Heart rate, MAP, SBP, DBP)	2. Post operative AKI(S. Creatinine, BUN)

Trial Locations

Locations (1)

Indira Gandhi institute of medical sciences; 🇮🇳 Patna, BIHAR, India

Indira Gandhi institute of medical sciences

🇮🇳Patna, BIHAR, India

Dr Sarthak Misra

Principal investigator

8210641979

drsarthakmisra2021@gmail.com