Registry of Effects of high-dose statins on Contrast induced nephropathy in patients of Acute Myocardial Infarctio
- Conditions
- Diseases of the circulatory system
- Registration Number
- KCT0003703
- Lead Sponsor
- Kangbuk Samsung Medical Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 460
[Inclusion Criteria]
1) Male and Female aged 20 or over
2) Non-ST elevation MI or STEMI
3) Atorvastatin(40mg) or Rosuvastatin(20mg) used for the reduction of cholesterol
4) High-intensity statin(atorvastatin 40mg, 80mg, rosuvastatin 20mg) never used or statin-naive
**Including intensity of below moderate statin.
(moderate intensity statins: rosuvastatin 10mg, atorvastatin 20mg, simvastatin/ezetimibe(vytorin) 10/20mg, simvastatin 40mg, pitavastatin 2mg, fluvastatin XL 80mg, pravastatin 40mg)
[Exclusion Criteria]
1) Cardiogenic shock
2) Iodinated contrast media administration within the previous 10 days
3) high-intensity statin being used(rosuvastatin 20mg, atorvastatin 40mg or 80mg)
4) Current hemo-dialysis or peritoneal dialysis
5) Thyroid diseases
6) An allergy to the radiocontrast medium
7) Patients who should ban statin
8) Pregnancy
9) Refusal of consent
Study & Design
- Study Type
- Observational Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Difference of the incidence of cystatin C-based contrast-induced nephropathy within 48 hours between the two groups
- Secondary Outcome Measures
Name Time Method Difference of the incidence of cystatin C-based contrast-induced nephropathy within 72 hours between the two groups