Treatment in the Rotterdam Early Arthritis CoHort. A stratified, randomised clinical trial in patients with recent-onset arthritis.
Completed
- Conditions
- Rheumatoid Arthritis, recent onset arthritis
- Registration Number
- NL-OMON23237
- Lead Sponsor
- Erasmus medical Centre RotterdamDepartment of Rheumatologie
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 810
Inclusion Criteria
1. Participant of the REACH cohort (patients with inflammatory joint complaints less then 1 year);
2. All patients must at least have one (out of 66) swollen joint.
Exclusion Criteria
1. Definite diagnosis of crystal arthropathy, (post)infective arthritis or autoimmune rheumatic disorder;
2. Previous therapy with DMARD's or corticosteroids;
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Functional ability as measured by HAQ and disease activity score (DAS) over time (area under the curve);<br /><br>2. Progression of radiological joint damage as measured by Sharp/van der Heijde score.
- Secondary Outcome Measures
Name Time Method 1. ACR arthritis core-set;<br /><br>2. Quality of Life, as measured with, SF-36, EuroQol;<br /> <br>3. Costs.