Treatment in the Rotterdam Early Arthritis CoHort

Recruiting

• Conditions: Rheumatoid Arthritis; 10023213

• Registration Number: NL-OMON38216
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 18 June 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 1080

Inclusion Criteria

To be able te sign informed consent
-Patients must meet the inclusion criteria for the REACH. That is: object arthritis, pain and or limitation of motion in 2 or more joints in combination with 2 of the following criteria: morningstiffness, tangential pain in MTP/MCP, pos fam anamneses, symm presentation, unexplained fatigue.

Exclusion Criteria

Complaints> 1 year by trauma or overload, no possibility to communicate, definitive diagn of gout, infectious arthritis or systematic disease, use of antirheumatic preparates before start study, contra indication for medication.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>•Primary endpoints: Disease activity:<br /><br><br /><br>Disease activity:<br /><br>Area under the curve (AUC) DAS<br /><br><br /><br>Functionality:<br /><br>AUC HAQ during 1 year of therapy<br /><br><br /><br>Joint damage:<br /><br>Radiologic progression </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>•Secondary endpoints:<br /><br><br /><br><br /><br>Absence of arthritis<br /><br>WHO/ILAR Core-set<br /><br>Self-assessed disease activity (RADAI)<br /><br>Cost (medical direct/indirect)<br /><br>Mediation reduction in time </p><br>