Comparative Evaluation of Diffusion Weighted MRI And Ultrasonography In The Detection of Breast Lesions
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Breast LN
- Sponsor
- Superior University
- Enrollment
- 108
- Locations
- 1
- Primary Endpoint
- Sensitivity and Specificity
- Status
- Active, not recruiting
- Last Updated
- last year
Overview
Brief Summary
This study aims to conduct a comparative evaluation of Diffusion Weighted MRI (DW-MRI) and Ultrasonography (US) in detecting breast lesions. Breast cancer remains a leading cause of cancer-related deaths among women worldwide, necessitating efficient and accurate diagnostic methods. Ultrasonography, a commonly used imaging modality, provides valuable insights into breast lesions but has limitations in sensitivity and specificity.
Detailed Description
Diffusion Weighted MRI, on the other hand, shows potential for higher accuracy in identifying malignant versus benign lesions due to its ability to assess tissue cellularity and integrity non-invasively. This research will involve a specified number of female participants within a defined age range, focusing on the comparative effectiveness, sensitivity, and specificity of DW-MRI and US. The findings are expected to contribute valuable insights into optimizing breast cancer diagnostic protocols, ultimately aiding in earlier detection, better patient outcomes, and possibly reducing the need for invasive biopsy procedures.
Investigators
Muhammad Naveed Babur
Principal Investigator
Superior University
Eligibility Criteria
Inclusion Criteria
- •Women with suspected breast lesions
- •Breast feeding woman
- •Referred for MRI examination.
- •Age 18 years or older
- •Ability to provide informed consent.
Exclusion Criteria
- •Contraindications to MRI or contrast agent
- •Previous breast Implant
- •Early Pregnancy
- •Exclusion criteria
Outcomes
Primary Outcomes
Sensitivity and Specificity
Time Frame: 12 Months
* Ultrasonography (USG): BI-RADS classification. * Diffusion Weighted MRI (DWI): Apparent Diffusion Coefficient (ADC) values. * Scales/Measurements: * Sensitivity (%): Formula: (True Positives) ÷ (True Positives + False Negatives) × 100 * Specificity (%): Formula: (True Negatives) ÷ (True Negatives + False Positives) × 100