Comparision Of Recovery Quality after giving Intravenous Lignocaine and Intravenous Fentanyl In Patients Undergoing Nasal Surgery Under General Anaesthesia

Phase 3

Not yet recruiting

Conditions: Chronic sinusitis, unspecified,

Registration Number: CTRI/2025/04/085618

Lead Sponsor: Department Of Anaesthesia Sawai Man Singh Medical College And Attached Hospital Jaipur

Brief Summary: This Prospective randomised controlled trial aims to compare the effects of Intravenous Lignocaine versus Intravenous Fentanyl on postoperative recovery qualit in patients undergoing Functional Endoscopic Sinus Surgery FESS Under General anaesthesia Both drugs are commonly used for I trapper active analgesia and modulation of peri operative stress responses

Sixty patients aged 18 to 60 years classified as ASA Physical status I or II scheduled for elective FESS will be randomly allocated into two groups Gruop L will receive intravenous lignocaine 1.5mg/ kg bolus followed by 2mg/kg/hour infusion and Group F will receive Intravenous fentanyl 2 mcg/kg bolus followed by 0.5 mcg/kg/hour infusion till end of surgery

The primary outcome will be the Quality of recovery QoR 15 score at 24 hours postoperatively Secondary outcomes include time to first rescue analgesia with total number of analgesic doses in 24 hours and to assess the Numerical Rating Scale Score at various time intervals between the two study groups and to compare the adverse effects such as nausea vomiting bradycardia hypotension between the two groups

This study seeks to determine whether lignocaine a non opioid analgesic with anti inflammatory and anti hyper Algeria properties can provide superior recovery outcomes compared to the conventional opioid Fentany in ENT surgeries

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 60

Inclusion Criteria

Informed written consent Age 18 to 60 years Elective Functional Endoscopic Sinus Surgery under General anaesthesia ASA GRADE I AND II.

Exclusion Criteria

Known hypersensitivity to local anaesthetics Body mass index greater than 30kg/m2 Patients with clinically significant neurological psychiatric or cardiovascular or renal and hepatic diseases History of alcoholic or drug abuse Patients who received an opioid medication within a 24 hour period before surgery.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Quality of Recovery score QoR 15 postoperatively	At 24 hours

Secondary Outcome Measures

Name	Time	Method
To Compare the postoperative analgesia duration and total number of doses in 24 hours between the two study groups	24hours
To compare the adverse effects between the two groups if any
To assess Numercal rating scale score at various time intervals between the two study groups	At 30mintes 6 hours 12 hours 24 hours

Trial Locations

Locations (2): Charak Bhavan ENT OT second floor
🇮🇳
Jaipur, RAJASTHAN, India
Sawai Man Singh Medical College And Attached Hospital
🇮🇳
Jaipur, RAJASTHAN, India
Charak Bhavan ENT OT second floor
🇮🇳Jaipur, RAJASTHAN, India
Dr Potharlanka Jeevana
Principal investigator
8500253219
jeevanapotharlanka@gmail.com