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Small Bowel Cleansing Prior to Video Capsule Endoscopy Examination

Phase 4
Completed
Conditions
Endoscopy
Interventions
Drug: Clear fluids
Drug: Picosalax
Registration Number
NCT00677794
Lead Sponsor
Queen's University
Brief Summary

There remains debate regarding whether small bowel cleansing is required prior to video capsule endoscopy, and if so, which method is best. This study prospectively tests cleansing with no preparation, preparation with picosalax, and preparation with polyethylene glycol.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
198
Inclusion Criteria
  • patients undergoing VCE.
Exclusion Criteria
  • bowel obstruction or ileus;
  • known stricture or fistula;
  • previous small bowel surgery;
  • severe gastroparesis or motility disorder
  • renal impairment (serum creatinine over normal range within three months of study);
  • congestive heart failure;
  • cirrhosis;
  • implanted cardiac pacemaker or defibrillator or other electromedical device;
  • pregnancy.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
1Clear fluidsClear fluids only after lunch.
2PicosalaxTwo sachets of picosalax the evening prior to Video Capsule Endoscopy (VCE).
3Polyethylene glycolPolyethylene glycol, 2 liters the evening prior to Video Capsule Endoscopy (VCE).
Primary Outcome Measures
NameTimeMethod
small bowel cleansingduring exam
Secondary Outcome Measures
NameTimeMethod
yield of Video Capsule Endoscopy (VCE) in iron deficiencyduring study
effect of preparation on blood chemistry24 hours after ingestion
tolerance of preparationduring preparation

Trial Locations

Locations (1)

Hotel Dieu Hospital

🇨🇦

Kingston, Ontario, Canada

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