Lung Protective Ventilation During Pulmonary Lobectomy in Children
Not Applicable
Completed
- Conditions
- Pulmonary Complication
- Registration Number
- NCT02680925
- Lead Sponsor
- Seoul National University Hospital
- Brief Summary
The investigator will evaluate the influence of lung protective ventilation on postoperative clinical outcome in pediatric patients. The hypothesis is that application of low tidal volume, intermittent alveolar recruitment and adequate positive end-expiratory pressure (PEEP) would be more beneficial than conventional ventilation in children.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 114
Inclusion Criteria
- Children who are scheduled for lung lobectomy under general anesthesia
- ASA physical status I, II
Exclusion Criteria
- History of airway or pulmonary interstitial disease
- Active URI
- Systemic inflammatory response disease
- cardiac disease
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method The number of patients with pulmonary complication up to postoperative 7 days The number of patients with pulmonary complication including atelectasis, pulmonary infiltration, pulmonary edema, pulmonary infection, pleural effusion and pulmonary embolism
- Secondary Outcome Measures
Name Time Method The number of patients with extrapulmonary complication through study completion, an average of 1 year Mean duration of mechanical ventilation through study completion, an average of 1 year Mean duration of ICU stay through study completion, an average of 1 year The number of patients with desaturation During surgery The number of patients with desaturation (SpO2 \< 90%)
Trial Locations
- Locations (1)
Seoul national university hospital
🇰🇷Seoul, Korea, Republic of
Seoul national university hospital🇰🇷Seoul, Korea, Republic of