Observational Study Evaluating the Impact of Lung Protective Ventilation (LPV) During Opioid Free Anesthesia (OFA) on Postoperative Oxygen Saturation.
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Oxygen Saturation
- Sponsor
- AZ Sint-Jan AV
- Enrollment
- 100
- Locations
- 1
- Primary Endpoint
- postoperative oxygen saturation
- Last Updated
- 6 years ago
Overview
Brief Summary
Observational study comparing patients with lung protective ventilation (LPV) following the consensus guidelines by Young C with patients getting routine lung ventilation, both during opioid free anesthesia (OFA).
Detailed Description
The paper by C Young et al describes the essential steps in protecting the lungs and preventing post operative pulmonary complications (PPC) like alveolar collapse. Alveolar collapse can be measured by oxygen saturation drop when no oxygen therapy is given, when full neuromuscular block (NMB) reversal and no opioid is given intra and postoperative. LPV means: tidal volume of 6 ml/kg, inspiratory-expiratory (I/E) ratio of 1/1, positive end expiratory pressure (PEEP) minimum 5 cmH20 and higher during laparoscopy in obese patients, Inspiratory oxygen concentration (FIO2) max 80% during induction and max 40 % during maintenance and extubation. Extubation in an awake, full NMB reversed patient getting no opioids while giving continuous positive airway pressure (CPAP) during withdrawal of the tube. Lung recruitment maneuver (LRM) when lung compliance decreases below 40 milliliter per centimeter water. (ml/cmH2O)
Investigators
Jan Mulier
MD PhD
AZ Sint-Jan AV
Eligibility Criteria
Inclusion Criteria
- •bariatric surgery
- •morbid obesity ( BMI \> 35)
Exclusion Criteria
- •patients with pre existing severe cardio-pulmonary diseases having oxygen saturation without oxygen below 94%.
Outcomes
Primary Outcomes
postoperative oxygen saturation
Time Frame: up to maximum 4 hours
saturation is continuously measured in the post anesthetic area without giving oxygen until sat drops below 94%.