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临床试验/CTRI/2025/10/096290
CTRI/2025/10/096290尚未招募2 期

A comparative clinical study of Guduchi Sheetkashay and Dhanyak Sheetkashay in the management of Garbhini Chardi in first trimester

Dr Neha Subhash Rathod1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2025年11月28日最近更新:

试验速览

阶段
2 期
状态
尚未招募
发起方
入组人数
60
试验地点
1
主要终点
To compare the efficacy of Guduchi Sheetkashay and Dhanyak Sheetkashay in the management of Garbhini Chardi in first trimester

研究概览

简要总结

This study is a randomized, open label comparing the efficacy of Guduchi Sheetkashat and Dhanyak Sheetkashay for 18 months in 60 patients with Garbhini Chardi.

Chardi is one of the Vyakta Garbha Lakshana.  This can be correlated with vomiting in pregnancy i.e. emesis gravidarum. Emesis gravidarum includes nausea associated with vomiting during the morning hours and sometimes continues throughout the day. Vomiting in pregnancy is a normal physiological change. Still it is important to monitor this problem during pregnancy. It may get converted to pathology if left untreated. So it should be treated as early as possible. The prevalence of this disease is 70%.

If it is not corrected on time it can cause increased intra-abdominal pressure which in turn causes threatened abortion, subchorionic bleeding. It can also cause maternal and fetal weight loss, antepartum haemorrhage, pre-eclampsia, low birth weight, prenatal death, fetal nutritional deficiency, Wernicke’s encephalopathy.

Garbha is totally dependent on mother for nutrition. Garbhini Chardi will affect the foetal growth.

Nutrition is best provided by enteral route. Orally liquid intake is necessary to prevent dehydration. Therefore giving Guduchi Sheetkashay  will be an appropriate management.

研究设计

研究类型
Interventional
分配方式
Coin toss, Lottery, toss of dice, shuffling cards etc
盲法
None

入排标准

年龄范围
18.00 Year(s) 至 35.00 Year(s)(—)
性别
Female

入选标准

  • All pregnant woman with Chardi in first trimester of pregnancy
  • Patients with pregnancy between 18-35 years of age
  • Patients willing for drug administration
  • Pregnant ladies with 3-4 episodes of vomiting.

排除标准

  • Patients with hyperemesis gravidarum ( more than 4 episodes of vomiting )
  • Patients in whom Chardi is seen in second and third trimester of pregnancy
  • Pregnant women with vomiting due to other systemic diseases such as intestinal obstruction, appendicitis, etc
  • Pregnant women with known case of diabetes mellitus
  • patients with multiple pregnancy
  • A known case of HIV, tuberculosis.

结局指标

主要结局

To compare the efficacy of Guduchi Sheetkashay and Dhanyak Sheetkashay in the management of Garbhini Chardi in first trimester

时间窗: Total duration of medication will be 15 days

次要结局

未报告次要终点

研究者

发起方
Dr Neha Subhash Rathod
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Dr Neha Subhash Rathod

Ashvin Rural Ayurved College, Manchi Hill, Ashvi Bk, Sangamner. Dist. Ahmadnagar

研究点 (1)

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