Testosterone gel in Depressio
Phase 1
- Conditions
- Depression,Hypogonadism.
- Registration Number
- IRCT20191211045698N1
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Male
- Target Recruitment
- 38
Inclusion Criteria
Depression(Hamilton Score =>12)
Not responded to a 6-week trial of antidepressant drugs
testosterone level less than 350ng/dl
Exclusion Criteria
Acute phase of psychotic symptoms including hallucinations and delusions
Bipolar disorder
drug addicted
Testosterone level > 350ng/dl
Suicide or attempted to suicide in the last 3 months
Dementia
PSA > 4ng/dl
Prostate cancer history
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Depression score in Hamilton questionnaire. Timepoint: before the intervention and 1 month, 2 months and 3 months after the start of testosterone gel. Method of measurement: Hamilton questionnaire.;Testosterone level. Timepoint: before the intervention and 1 month, 2 months and 3 months after the start of testosterone gel. Method of measurement: Blood test to measure testosterone level.
- Secondary Outcome Measures
Name Time Method Sexual function score. Timepoint: Before the intervention and 3 months after taking testosterone gel. Method of measurement: IIEF questionnaire.