Which aligners attract less bacteria?A study for better oral health

Not yet recruiting

• Conditions: Dental caries on smooth surface,

• Registration Number: CTRI/2025/06/089273
• Lead Sponsor: Maha srinithi

Brief Summary

Clear orthodontic retainers are widely used in India as an aesthetically appealing alternative to traditional wire retainers. However, the formation of biofilm on retainer surfaces can have detrimental effects on oral health. This study aimed to evaluate and compare the biofilm formation on three commercially available clear orthodontic aligners commonly used in India. Methods: Four clear orthodontic aligners materials, including Polyethylene Terephthalate Gycol(PETG),polyurethane,polyproylene.polymethyl methacrylate were selected for this experimental study. Standardized specimens of each aligner material were fabricated according to manufacturer guidelines.Sample will be collected from the patients after 24 hours of wear. Scanning electron microscopy (SEM) is utilized to analyze the morphology of biofilms and quantify bacterial adhesion on the aligner surfaces. Image analysis software will be  employed to assess biofilm coverage and thickness.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2025-06-17
• Study Start: 2025-10-07

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

patients with no maloclusion.

Exclusion Criteria

Below 18, poor oral hygiene, severely crowded dentition.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare the four different aligner materials based on adhesion property of biofilm	Asssesd at 24 hours of wear of aligners

Secondary Outcome Measures

Name	Time	Method
To analyse the adhesion properties among various aligner materials between male & female	Assesed at 24 hours of wear of aligners

Trial Locations

Locations (1)

Karpaga Vinayaga Institue of dental Sciences; 🇮🇳 Chennai, TAMIL NADU, India

Karpaga Vinayaga Institue of dental Sciences

🇮🇳Chennai, TAMIL NADU, India

Dr Maha Srinithi

Principal investigator

7010259598

srinithiselvaraj22@gmail.com