Enteral versus parenteral feeding in pediatric oncology patients with gastro-intestinal mucositis

Suspended

• Conditions: Child; Cancer; Mucositis; Nutrition

• Registration Number: NL-OMON29350
• Lead Sponsor: niversity Medical Center Groningen (UMCG), Beatrix Children's Hospital

Brief Summary

/A

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Suspended
• Sex: Not specified
• Target Recruitment: 25

Inclusion Criteria

Children(0-18 years of age) admitted to the University Medical Center Groningen for the treatment of acute myeloid leukemia(AML) or B-Non Hodgkin lymphoma(B-NHL). They receive chemotherapy according to the Dutch Childhood Oncology Group(DCOG), for both AML and B-NHL containing at least 2 identical chemotherapy courses.

Exclusion Criteria

-Patients and their parents are excluded when they are insufficiently capable of speaking and understanding the Dutch language.

-Patients are excluded when life expectancy is estimated to be below six months.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
-Nutritional state (weight, length, mid upper arm circumference)

Secondary Outcome Measures

Name	Time	Method
- The degree of mucositis measured by plasma citrulline<br /><br>- Quality of life (using Pedsqual questionnaire every 5 days and daily Cantrills ladder and VAS score)<br /><br>- Number of infectious complications<br /><br>- Number of bacteraemias<br /><br>- Percentage of calculated optimal quantity of tube feeding actually given<br /><br>- Liver toxicity scores according to NCI-CTCAE version 4.0<br /><br>- Length of hospital stay<br /><br>- Clinical symptoms of mucositis (NCI-CTCAE 4.0)