Feeding strategy during mucositis
Recruiting
- Conditions
- - Children- Cancer- Mucositis- Nutrition
- Registration Number
- NL-OMON29080
- Lead Sponsor
- niversity Medical Center Groningen(UMCG), Beatrix Children's Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 15
Inclusion Criteria
Children (0-18 yrs of age) admitted to the University Medical Center Groningen (UMCG) or Academic
Medical Center (AMC) Amsterdam, for treatment of B Non Hodgkin lymphoma (B-NHL), or autologous stem cell transplantation(SCT)
Exclusion Criteria
-
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Feeding strategy (tube feeding, tpn) and duration in days
- Secondary Outcome Measures
Name Time Method - Severity of mucositis measured by plasma citrulline (during regular vena punctures, no extra punctures will be done for study purpose only, the remaining plasma will be used to measure citrulline)<br /><br>- Number of days of mucositis >grade 1, and the peak severity of mucositis according to the NCI-CTCAE criteria<br /><br>- Weight, daily <br /><br>- Number of days with pain and the peak level of pain, daily measured with the VAS/Faces score<br /><br>- Days of analgesics, and the total amount of analgesics<br /><br>- The number of infectious complications and number of positive blood cultures<br /><br>- Length of hospital stay<br>