Using Functional Near-infrared Spectroscopy to Study the Changes in Brain Activity During Dual-task Walking and the Effects of Structured Cognitive-motor Exercise in Individuals With Stroke
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 84
- 试验地点
- 2
- 主要终点
- Dual-task gait speed
研究概览
简要总结
To assess the effects of a dual-task exercise program on cognitive-motor interference during dual-task walking and the associated changes in brain activity.
详细描述
Stroke is one of the leading causes of chronic disability in Hong Kong and other parts of the world. Mobility dysfunctions are among the most common impairments observed after stroke. Restoration of mobility is also a top priority in rehabilitation goal-setting by stroke patients. In daily life, functional ambulation in the community requires the ability to maintain walking balance while simultaneously engaging in other attention-demanding tasks (i.e., dual-tasking), such as walking when holding a conversation, or crossing the street while attending to traffic signals. There is increasing evidence that performing a cognitive task in conjunction with a mobility task would cause more severe degradation of one or both tasks among stroke patients when compared with age-matched able-bodied individuals. This phenomenon, termed "cognitive-motor interference", should warrant detailed study, since it has an important impact on community-living among people with stroke.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
盲法说明
This will be a single-blinded RCT. The assessor will be blinded during assessments. The participants and investigators (trainers) are not possible to be blinded as it is an exercise intervention.
入排标准
- 年龄范围
- 50 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diagnosis of stroke confirmed by brain scan reports
- •Community-living
- •Stroke onset ≥ 6 months
- •Aged 50 years or older
- •Modified Rankin scale 1-3
- •Capable of following verbal instructions
- •Montreal Cognitive Assessment score ≥ 22
- •Ability to walk for 1 min independently with or without a walking aid
- •Not receiving formal rehabilitation elsewhere
排除标准
- •Other neurological disorders
- •Pain or other comorbidities that seriously affect the ability to walk
- •Contraindications to exercise (e.g., angina).
结局指标
主要结局
Dual-task gait speed
时间窗: Through study completion, an average of 1 year
Gait speed under dual-task condition will be recorded
Dual-task cognitive performance
时间窗: Through study completion, an average of 1 year
Number of correct responses will be measured during dual-task walking
次要结局
- Oxyhemoglobin concentration changes of the brain(Through study completion, an average of 1 year)
- Dual-task gait performance 1(Through study completion, an average of 1 year)
- Dual-task gait performance 2(Through study completion, an average of 1 year)
- Dual-task gait performance 3(Through study completion, an average of 1 year)
研究者
Marco Yiu-Chung Pang
Chair professor
The Hong Kong Polytechnic University