Impact of androgen deprivation therapy on cognitive function in patients with prostate cancer.
Not Applicable
Recruiting
- Conditions
- Prostate cancer
- Registration Number
- JPRN-UMIN000042253
- Lead Sponsor
- Department of Urology, Kindai University Nara Hospital.
- Brief Summary
A total of 77 patients completed all scheduled assessments. Serum testosterone levels and MMSE scores were almost identical in the 2 cohorts at baseline. With 36-months follow up, significant decrease on the serum testosterone levels were observed in patients on ADT, but not in controls. As measured by MMSE, no statistically significant differences in cognitive function were observed at 6, 12 and 36 months compared to baseline in either cohort.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Male
- Target Recruitment
- 88
Inclusion Criteria
Not provided
Exclusion Criteria
1.Patients with active other malignancy. 2.Patients with or confirmed a history of cognitive impairment. 3.Patients with other serious disease or condition. 4.Patients deemed inappropriate by the attending physician.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method