Randomized study of Mechanical Thrombectomy vs. best medical treatment for stroke at 24 to 72 hours of Last Known Well

Not Applicable

Recruiting

• Conditions: Stroke; D000083244

• Registration Number: JPRN-jRCT1032230344
• Lead Sponsor: Kimura Kazumi

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2023-09-12
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 260

Inclusion Criteria

1. 20 years of age or older
2. Patients with acute stroke 24-72 hours after the last healthy check
3. Subjects with a pre-randomization NIHSS score of 6 or higher
4. Subjects with pre-onset modified Rankin Scale score of 2 or less
5. Subjects who can confirm ICA (cervical and intracranial) and M1 obstruction by MRA or CTA
6. Subjects who can undergo endovascular treatment promptly after randomization
7. Pre-allotment detailed DWI-ASPECTS (10-point scale) of 6 or more (ASPECTS are evaluated by detailed DWI-ASPECTS, which deducts points for M1-M6 with a high signal of 1/2 or more) or CT-ASPECTS of 6 or more
8. Subjects who explained this research using an explanation document and obtained written consent

Exclusion Criteria

1. Patients who are unsuitable for endovascular treatment, such as having a history of hypersensitivity to contrast media
2. Patients with serious renal disease (not limited to those on dialysis)
3. Patients who are Lactating, or who are or may be pregnant
4. Patients who are expected to have a life expectancy of 90 days or less
5. Patients with a history of hypersensitivity to contrast media and for whom endovascular treatment is inappropriate

Study & Design

• Study Type: Interventional
• Study Design: Not specified