A study to compare the efficacy in terms of preventing disease recurrence; and safety in terms of drug related side effects of Mycophenolate mofetil in comparison with Levamisole in children with difficult to treat nephrotic syndrome, a chronic protein loosing kidney disease.
Phase 3
Completed
- Conditions
- Health Condition 1: null- Nephrotic Syndrome
- Registration Number
- CTRI/2013/10/004107
- Lead Sponsor
- ilratan Sircar Medical College and Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 120
Inclusion Criteria
Children between 2years and16 years with FRNS with or without steroid dependency.
Estimated glomerular filtration rate (eGFR) >80 ml/min per 1.73 m2.
Children in remission at study entry (trace or nil proteinuria, as determined by the dipstick test or <100 mg/dl for at least 3 days).
No previous use of any steroid sparing agent.
Informed cosent.
Exclusion Criteria
Patients with severe leucopenia (leucocytes less than 3.0Ã? 1000 cells/mm3), severe anemia (haemoglobin less than 8.9 g/dl) or any active infection.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method