Simultaneous Lengthening of Bilateral Femora and Tibiae in Achondroplastic Patients
Not Applicable
Completed
- Conditions
- SHOX Gene With Short Stature
- Registration Number
- NCT01328418
- Lead Sponsor
- Bilen, Fikri Erkal, M.D.
- Brief Summary
The purpose of this study is to determine whether lengthening of both the tibiae and femora in achondroplastic patients is safe and provides reproducible outcome.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 22
Inclusion Criteria
- Achondroplasia, first lengthening period
Exclusion Criteria
- Previous lengthening
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method Paley's functional scoring system Minimum 2 year follow-up Paley's functional scoring system evaluates the results after lengthening or deformity correction procedures: residual limb length discrepancy, any brace or other aid usage, joint contracture, pain, soft tissue dystrophism
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
How does limb lengthening over nail influence bone regeneration in SHOX-related short stature patients?
What are the comparative outcomes of simultaneous vs sequential bilateral femoral and tibial lengthening in achondroplasia?
Which genetic biomarkers predict successful limb lengthening in patients with SHOX gene mutations?
What long-term complications arise from simultaneous bilateral limb lengthening using intramedullary nails in achondroplasia?
How do growth hormone therapies compare to surgical lengthening for managing SHOX-related short stature?
Trial Locations
- Locations (1)
Istanbul Medical School
🇹🇷Istanbul, Turkey
Istanbul Medical School🇹🇷Istanbul, Turkey