In babies less than 28 days, nebulization with epinephrine after removing baby from ventilator versus no nebulization: A Randomized control study
Not Applicable
- Conditions
- Health Condition 1: P84- Other problems with newborn
- Registration Number
- CTRI/2023/05/052241
- Lead Sponsor
- Department of Neonatology Lok Nayak hospital Delhi
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
All the neonates who at the time of extubation have been ventilated for more than 2 completed days.
Exclusion Criteria
1.Vocal cord anomalies and another anatomic abnormality of the upper airways before intubation as noticed and recorded during intubation.
2.Seconde extubation.
3. Previous use of epinephrine in neonates during hospitalization or prior to extubation.
4. Silverman Anderson score 0/10 immediately after extubation with no evidence of hypoxemia on pulse oximeter in room air over 15 minutes.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To determine the role of epinephrine nebulization in addition to standard care in successfully preventing extubation failure in term and preterm neonates.Timepoint: 48 hours after extubation
- Secondary Outcome Measures
Name Time Method To determine the advantage of using post extubation epinephrine nebulization in term and preterm neonates with regard to; duration of post-extubation noninvasive respiratory support, hospital stay, time to reintubation. <br/ ><br>To determine occurrence of death, laryngeal edema, VAP, sepsis, any side effects of nebulized epinephrine.Timepoint: 28 days