Comparative Study on the Clinical Efficacy and Analgesic Mechanism of External Application of Traditional Chinese Medicine Huoxue Ointment and Western Medicine Ibuprofen Cream in the Treatment of Early Knee Osteoarthritis Pai
- Conditions
- Knee osteoarthritis
- Registration Number
- ITMCTR2100004220
- Lead Sponsor
- Beijing Tiantan Hospital Affiliated to Capital Medical University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- Not specified
1. Patients with knee osteoarthritis of Western medicine and arthralgia syndrome of traditional Chinese medicine;
2. Patients aged 40-60 years;
3. Patients with knee pain as the chief complaint;
4. Patients without koa systematic treatment within two weeks;
5. Patients who signed informed consent.
1. Patients with skin injury of the affected knee joint;
2. Patients with skin drug allergy constitution or known allergic to external use of the drug ingredients;
3. Patients during pregnancy and lactation;
4. Patients who are participating in clinical trials of other drugs;
5. Patients who have to take NSAIDs or glucocorticoids for other reasons;
6. Patients with severe heart, lung, brain, liver, kidney and hematopoietic system diseases and mental disorders;
7. Patients with poor compliance due to other reasons.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ??????;Constructing the PRO Scale for Knee Osteoarthritis Based on the TCM Syndrome Differentiation;WOMAC Osteoarthritis Index score;
- Secondary Outcome Measures
Name Time Method erythrocyte sedimentation rate;Dosage for remedial use of NSAIDs;liver function;High-throughput chip inflammatory response and bone metabolism indicators;Blood routine test;X-ray examination;C-reactive protein;Kidney function;