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Pilot Feasibility Study for HypoPals, a Mobile Health Program for Improving Hypoglycemia Management.

Not Applicable
Active, not recruiting
Conditions
Type 1 Diabetes
Hypoglycemia
Interventions
Behavioral: Basic Education
Behavioral: Education Plus
Behavioral: Hypoglycemia Symptom Detection Training
Registration Number
NCT05916131
Lead Sponsor
University of Michigan
Brief Summary

A mobile health program "HypoPals", which incorporates data from continuous glucose monitoring systems (CGMs) and sends personalized text messages to help people sharpen their low blood sugar symptom detection skills, and help people consider how they think of low blood sugar, was devised. The goal of the current study is to make sure that HypoPals runs smoothly, users find the intervention useful, and the way the researchers conduct the final study will be correct (i.e., there is a need for 'pilot testing' the developed technology and research methods).

All participants will receive basic hypoglycemia education text messages, and then be randomized to one of the four experimental conditions: Hypoglycemia Symptom Detection Training, Education Plus, both Symptom Detection Training and Education Plus, and usual care. Participants may receive additional interventional text messages based on the experimental condition participants are assigned to.

The study may terminate after collecting sufficient data to evaluate the primary outcome (i.e., determining the number of participants recruited to reach 20 participants who complete the intervention).

Detailed Description

Not available

Recruitment & Eligibility

Status
ACTIVE_NOT_RECRUITING
Sex
All
Target Recruitment
40
Inclusion Criteria
  • Signed and dated informed consent form
  • Self-reported diagnosis of type 1 diabetes for at least 5 years
  • Previous attendance of structured diabetes education program
  • Using CGM greater or equal to (≥1) year
  • Ongoing Dexcom CGM use time ≥70% based on CGM report at screening
  • Have had experienced ≥1 episode of severe hypoglycemia in the past year while using CGMs or spending ≥1% of time in level 2 hypoglycemia at the time of pre-screening
  • Using cellphone with functionality for sharing real-time data to Dexcom Clarity and receiving text messages
  • Be able to communicate in English (spoken and written)
  • Willing to comply with all study procedures including sharing CGM glucose information, receiving and reading intervention text messages, and completing study questionnaires
Exclusion Criteria
  • Active participation in clinical trials on diabetes/hypoglycemia interventions
  • Pregnancy or planning for pregnancy within a year
  • Untreated adrenal insufficiency or hypothyroidism
  • Uncontrolled mental disorder or chronic cognitive dysfunctions (include but not limited to uncontrolled schizophrenia, depression and bipolar disorders; learning disability; active alcohol and substance dependence; dementia or cognitive impairment independent of hypoglycemia)

Study & Design

Study Type
INTERVENTIONAL
Study Design
FACTORIAL
Arm && Interventions
GroupInterventionDescription
Education PlusEducation PlusTo provide Education Plus intervention.
Education PlusBasic EducationTo provide Education Plus intervention.
Hypoglycemia Symptom Detection TrainingBasic EducationTo provide Hypoglycemia Symptom Detection Training intervention.
Hypoglycemia Symptom Detection Training and Education PlusBasic EducationTo provide both Hypoglycemia Symptom Detection Training and Education Plus interventions simultaneously.
Usual CareBasic EducationContinuing usual care after basic education.
Hypoglycemia Symptom Detection TrainingHypoglycemia Symptom Detection TrainingTo provide Hypoglycemia Symptom Detection Training intervention.
Hypoglycemia Symptom Detection Training and Education PlusHypoglycemia Symptom Detection TrainingTo provide both Hypoglycemia Symptom Detection Training and Education Plus interventions simultaneously.
Hypoglycemia Symptom Detection Training and Education PlusEducation PlusTo provide both Hypoglycemia Symptom Detection Training and Education Plus interventions simultaneously.
Primary Outcome Measures
NameTimeMethod
The number of participants recruited to reach 20 participants that complete the interventionApproximately 1 year (recruitment period)

This number will include participants that were enrolled and received part or all of the intervention.

Secondary Outcome Measures
NameTimeMethod
Number of patients contacted during the entire recruitment periodApproximately 1 year (recruitment period)
Rate of participant retention at 26 weeks6 months
Percentage of participants with continuous glucose monitoring (CGM) data collected at 12 weeks12 weeks
Percentage of contacted patients being eligible and consentedApproximately 1 year (recruitment period)
Rate of participant retention at 12 weeks12 weeks
Percentage of participants with continuous glucose monitoring (CGM) data collected at 52 weeks1 year
Percentage of participants reporting reading message content at the end of the intervention12 weeks
Rate of participant retention at 52 weeks1 year
Percentage of participants with continuous glucose monitoring (CGM) data collected at 26 weeks6 months
Percentage of participants finding message content helpful (positive) at the end of the intervention12 weeks

The outcome will be determined as positive/negative and the study team will report the percent of participants reporting positive outcome.

Trial Locations

Locations (1)

University of Michigan

🇺🇸

Ann Arbor, Michigan, United States

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