Comparing the Prognosis of Patients With Cardia and Non-cardia Gastric Cancer.

Recruiting

• Conditions: Gastric Cancer
• Interventions: Other: Cardia and Non-cardia gastric cancer

• Registration Number: NCT03895008
• Lead Sponsor: Affiliated Hospital of Qinghai University

Brief Summary

To comparing the stage-for-stage prognosis of patients with cardia and non-cardia gastric cancer after operation.

Detailed Description

The aim of this study is to compare the stage-for-stage prognosis of patients with cardia and non-cardia gastric cancer after operation.In this study, patients with cardiac and non-cardiac gastric cancer who undergo radical resection from January 2019 to December 2024 will be included. We will follow up the patient's progression, recurrence time and survival time.

Study Timeline

• Status Verified: 2019-03
• Study First Submitted: 2019-03-28
• Study First Submitted QC: 2019-03-28
• Study First Posted: 2019-03-29
• Last Update Submitted: 2019-07-02
• Last Update Posted: 2019-07-05
• Study Start: 2019-07-08
• Primary Completion: 2023-12-31
• Study Completion: 2024-12-31

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 1000

Inclusion Criteria

1. Histopathology or cytopathology proven cardia or non-cardia gastric cancer;

2. Operable gastric cancer patients: primary lesions can be completely excision, no distant metastasis;

3. Life expectancy of at least 6 months;

4. ECOG（Eastern Cooperative Oncology Group ） score 0-1;

5. Age: 18~80 years old;

6. Normal hemodynamic indices before the recruitment (including blood cell count and liver/kidney function).

   For example: WBC（White blood cell count ）>4.0×109/L; NEU（Neutrophils）>1.5×109/L; PLT（Platelet）>100×109/L;

7. Roughly normal cardiopulmonary function: No coronary heart disease, myocardial infarction, pulmonary heart disease, refractory hypertension;

8. Not concomitant with other uncontrollable benign diseases before the recruitment;

9. Voluntarily signed the informed consent.

Exclusion Criteria

1. Advanced gastric cancer patients with distant metastasis and inoperable ;
2. Pregnant or lactating women;
3. Patients who have no desire to participate in the study.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Non-cardia gastric cancer	Cardia and Non-cardia gastric cancer	Non-cardia gastric cancer is defined as tumors originated from the gastric mucosa distal to the cardia.
Cardia gastric cancer	Cardia and Non-cardia gastric cancer	Cardiac gastric cancer is defined as a cancer center lies arising 2-5 cm from the gastric mucosa distal to the esophagogastric junction.

Primary Outcome Measures

Name	Time	Method
Disease Free Survival（DFS）	5 years	The time from the primary operation to disease recurrence or death.

Secondary Outcome Measures

Name	Time	Method
Overall survival(OS)	5 years	OS is defined as the time from the end of radical surgery to death for any reason or at the last follow-up.

Trial Locations

Locations (3)

The Second Hospital of Lanzhou University; 🇨🇳 Lanzhou, Gansu, China

Affiliated Hospital of Qinghai University; 🇨🇳 Xining, Qinghai, China

People's Hospital of Qinghai Province; 🇨🇳 Xining, Qinghai, China