Ultra High Field Magnetic Resonance Imaging as a Biomarker for Premotor Parkinson's Disease

Oregon Health and Science University1 site in 1 country18 target enrollmentSeptember 2015

ConditionsParkinson Disease REM Sleep Behavior Disorder

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Parkinson Disease
Sponsor: Oregon Health and Science University
Enrollment: 18
Locations: 1
Primary Endpoint: Quantitative signal analysis of nigrosome 1
Last Updated: 6 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

This is a prospective observational study investigating the utility of 7 Tesla MRI to quantify nigrosome1 signal in a cohort of individuals with recent onset Parkinson's disease and in at-risk cohorts at a premotor state of Parkinson's disease.

Registry

clinicaltrials.gov

Start Date

September 2015

End Date

January 2021

Last Updated

6 years ago

Study Type

Observational

Sex

All

Investigators

Sponsor

Oregon Health and Science University

Responsible Party

Principal Investigator

Matthew Brodsky

Associate Professor of Neurology

Oregon Health and Science University

Eligibility Criteria

Inclusion Criteria

•Idiopathic Parkinson's disease within 1 year of motor symptom onset. Idiopathic REM sleep behavior disorder without signs/symptoms of Parkinson's disease.
•Age-matched controls.