临床试验/NCT03288909

NCT03288909Unknown不适用

Ultra High Field Magnetic Resonance Imaging as a Biomarker for Premotor Parkinson's Disease

Oregon Health and Science University1 个研究点分布在 1 个国家目标入组 18 人开始时间: 2015年9月最近更新: 2019年6月24日

适应症

试验速览

阶段: 不适用
发起方: Oregon Health and Science University
入组人数: 18
试验地点: 1
主要终点: Quantitative signal analysis of nigrosome 1

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

This is a prospective observational study investigating the utility of 7 Tesla MRI to quantify nigrosome1 signal in a cohort of individuals with recent onset Parkinson's disease and in at-risk cohorts at a premotor state of Parkinson's disease.

研究设计

研究类型: Observational
观察模型: Case Control
时间视角: Prospective

入排标准

年龄范围: 18 Years 至 —（Adult, Older Adult）
性别: All
接受健康志愿者: 是

入选标准

•Idiopathic Parkinson's disease within 1 year of motor symptom onset. Idiopathic REM sleep behavior disorder without signs/symptoms of Parkinson's disease.
•Age-matched controls.

排除标准

•Atypical Parkinsonism
•Contraindications for MRI

结局指标

主要结局

Quantitative signal analysis of nigrosome 1

时间窗: 1 year

次要结局

Change in quantitative signal analysis of nigrosome 1(3 years)

研究者

发起方

Oregon Health and Science University

申办方类型

Other

责任方

Principal Investigator

主要研究者

Matthew Brodsky

Associate Professor of Neurology

Oregon Health and Science University

研究点 (1)

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