Efficacy of Vicryl Rapide suture on the reduction of the scar formation after upper jaw surgery
- Conditions
- Clinical evaluation of mucosal scar in maxillary vestibule using vicryl and vicryl rapide suture materials after Le-fort I osteotomy.Surgical instruments, materials and general hospital and personal-use devices (including sutures) associated with adverse incidentsY74.3
- Registration Number
- IRCT20131205015665N5
- Lead Sponsor
- Esfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 26
patients undergoing Le-fort I osteotomy for correction of skeletal deformity
age less than 18 or more than 40
pre-existing scar in vestibular area or history of surgery in maxillary vestibule
any systemic and chronic disease which can interfere with wound healing process (i.e. diabetes, kidney and liver diseases)
long-term corticosteroid or antibiotic therapy, or immunosuppressor drugs (specially in the last 6 month)
congenital or acquired compromising immune system
dehydration and malnutrition and associated neural defects (especially vitamin C and zinc deficiency)
history of radiotherapy and using cytotoxic drugs
tobacco use and alcoholism
Fitzpatrick skin classification types I, IV, V, VI
Maxillary advancement more than 6 mm
history of allergic reaction (known or suspected) to suture materials
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Mean score of mucosal scarring index from 0 to 10. Timepoint: 4 months after surgery. Method of measurement: using mucosal scarring index consisting of 5 parts of Width, Height or Contour, Color, Suture mark, and Overall appearance; each range from 0 to 2 scores. For reach patient, 3 surgeons will evaluate the tissue and the mean of scores will be reported for the left and right sides for each patient.
- Secondary Outcome Measures
Name Time Method