Hyperbaric oxygen therapy for benign anastomotic esophageal strictures: a pilot study
- Conditions
- benign recurrent or refractory anastomotic strictures as a result of esophagectomy. Benign anastomic strictureesophagectomyBenigne anastomose strictuuroesofagectomie
- Registration Number
- NL-OMON26778
- Lead Sponsor
- niversity Medical Center Utrecht
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 10
Inclusion Criteria
Benign esophageal anastomotic stricture; defined as a stenosis at the esophagogastric anastomosis causing clinically significant dysphagia.
-Clinically significant dysphagia; defined as grade 2 or worse on the Ogilvie scale
Exclusion Criteria
-Known or strongly suspected esophageal motility disorder
-Known or strongly suspected malignant stricture
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To assess the effect of hyperbaric oxygen therapy on the mucosal capillary hemoglobin oxygen saturation levels in the esophagus and the gastric tube
- Secondary Outcome Measures
Name Time Method - To assess the effect of hyperbaric oxygen therapy on: <br /><br>- dysphagia symptoms <br /><br>- quality of life (QLQ-C30 + OES 18)<br /><br>