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Clinical Trials/NCT05593159
NCT05593159
Completed
Not Applicable

Evaluating the Clinical Performance of a Bioactive Restorative Material in Non-Carious Cervical Lesions

Damascus University1 site in 1 country30 target enrollmentMay 15, 2022
ConditionsCervical Lesion

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Cervical Lesion
Sponsor
Damascus University
Enrollment
30
Locations
1
Primary Endpoint
Change in retention rate
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

Evaluating the clinical performance of a bioactive restorative materiel (Cention N) placed in non-carious cervical lesions (NCCLs) with no preparation and 1-step adhesive system or, with preparing a gingival retentive groove and no adhesive system.

Detailed Description

Cention N is a relatively new restorative material that is known to be the first commercially available bioactive resin composite. The manufacturing company recommends using Cention N with 1-step adhesive system in non-retentive cavities, or with no adhesive system in retentive cavity preparations. This study was designed to evaluate the clinical performance of this material in non-carious cervical lesions by comparing it to RM-GIC (Fuji II LC). Information about oral and tooth brushing habits along with detailed information about the characteristics of each NCCL, gingival status, and preoperative sensitivity will be collected for each patient.

Registry
clinicaltrials.gov
Start Date
May 15, 2022
End Date
November 1, 2023
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Good general health
  • with at least 20 teeth under occlusion
  • Should have three or more NCCLs which share the characteristics of being deeper than 1 mm, and involve both the enamel and dentin of vital teeth without mobility

Exclusion Criteria

  • Poor oral hygiene
  • Severe periodontitis
  • Severe bruxism habits
  • Xerostomia

Outcomes

Primary Outcomes

Change in retention rate

Time Frame: Baseline: 1 week, follow-ups after 3 months, 6 months, 9 months, 1 year

Rated by Modified United States Public Health Service criteria (USPHS) Alpha: Retained. Bravo: Partially retained. Charlie: Missing.

Secondary Outcomes

  • Change in marginal adaptation(Baseline: 1 week, follow-ups after 3 months, 6 months, 9 months, 1 year)
  • Change in surface texture(Baseline: 1 week, follow-ups after 3 months, 6 months, 9 months, 1 year)
  • Change in secondary caries(Baseline: 1 week, follow-ups after 3 months, 6 months, 9 months, 1 year)
  • Change in restoration fracture(Baseline: 1 week, follow-ups after 3 months, 6 months, 9 months, 1 year)
  • Change in anatomic form(Baseline: 1 week, follow-ups after 3 months, 6 months, 9 months, 1 year)
  • Change in marginal discoloration(Baseline: 1 week, follow-ups after 3 months, 6 months, 9 months, 1 year)
  • Change in patient satisfaction(Baseline: 1 week, follow-ups after 3 months, 6 months, 9 months, 1 year)
  • Change in post-operative sensitivity with stimulation(Baseline: 1 week, follow-ups after 3 months, 6 months, 9 months, 1 year)
  • Change in post-operative sensitivity without stimulation(Baseline: 1 day, follow-ups after 1 week, 1 month, 3 months, 6 months, 9 months, 1 year)

Study Sites (1)

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