A clinical study comparing outcome of regenerative root canal treatment with and without chitosan loaded triple antibiotic paste.
- Registration Number
- CTRI/2024/03/064482
- Lead Sponsor
- Dr.Asiya Mujawar
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
1. patients in the age range of 18–30 years without systematic disease/allergic reactions
2. Nonvital single- rooted teeth (anterior or premolars) encasing 1 root canal with mature roots (closed apices) and a periapical lesion score =3 according to Ostravik et al.
Score 1: Normal periapical structure
Score 2: Small changes in bone structure
Score 3: Changes in bone structure with mineral loss
Score 4: Periodontitis with well-defined radiolucency
Score 5: Severe periodontitis with exacerbating factors
1. Medically compromised patients (with immunosuppressive/systemic diseases, patients on medications) - periodontologically compromised teeth.
2. Endodontically treated teeth
3. Teeth with periapical lesions more than 5 mm in diameter.
4. Patients who refuse to participate.
5. Anatomical variations leading to inability to reach the full working length.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To evaluate the regenerative potential of pulp in necrotic mature teeth with and without chitosan loaded triple antibiotic paste.Timepoint: The outcome will be assessed at 6months and 1 year .
- Secondary Outcome Measures
Name Time Method Vitality of toothTimepoint: the vitality of the tooth will be assessed with electric pulp testing device after 6 months and 1 year of the treatment