Comparison of the effectiveness of 2 cervical ripening agents Oral Mifepristone and vaginal Isosorbide Mononitrate (IMN) for induction of labor in pregnant women with gestational age 28 to 34 weeks.
Phase 2
- Conditions
- Health Condition 1: O619- Failed induction of labor, unspecified
- Registration Number
- CTRI/2023/06/053401
- Lead Sponsor
- Dr Meeta Pandit
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.All 28 to 34 weeks pregnancy who need Induction of labor for obstetrics and maternal indications.
2.Bishops score less than 4.
3.Those giving consent.
Exclusion Criteria
1.Contraindications to vaginal birth.
2.Hypersensitivity to Mifepristone and IMN.
3.Contraindications to Mifepristone and IMN.
4.Those not giving consent.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Improvement in Bishops Score <br/ ><br>Duration between administration of cervical ripening agents and delivery <br/ ><br>Failed induction is after 2 doses of misoprostol 3hrs apart <br/ ><br>Timepoint: at baseline <br/ ><br>after 6hrs <br/ ><br>after 12hrs <br/ ><br>at 15 hrs <br/ ><br>at 18 hrs
- Secondary Outcome Measures
Name Time Method Mode of deliveryTimepoint: Failed induction is after 2 doses of misoprostol 3h apart