Clinical, Bacterial, and Inflammatory Outcomes of Indocyanine Green-mediated Photodynamic Therapy for Treating Periimplantitis Among Diabetic Patients: a Randomized Controlled Clinical Trial
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 2
- 主要终点
- Probing depth
研究概览
简要总结
In this study, the effect of photodynamic therapy (indocyanine green mediated) on the clinical, biological and inflammatory aspects was assessed in diabetic patients having peri-implantitis
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 45 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •adult patients above 45 years of age having type 2 DM
- •HbA1c (≥6.5%) and fasting glucose test
- •probing depth ≥6 mm with bleeding and/or suppuration on at least one site around dental implants that remained in situ
- •On radiographic assessment, the implants exhibited ≥ 3 mm alveolar bone loss apical to the coronal region of the intraosteal portion of the dental implant.
- •Exclusion Criteria Patients were excluded if they indicated current or former history of tobacco smoking, any systemic disease other than DM, enrolled in a non-surgical periodontal maintenance program, history of implant repair, pregnancy, and part six months use of antimicrobials, non-steroidal anti-inflammatory drugs, bisphosphonates, or corticosteroids.
排除标准
- 未提供
结局指标
主要结局
Probing depth
时间窗: 6 months
Measurement of consecutive millimeter markings of the periodontal pocket depth
Suppuration
时间窗: 6 months
Presence or absence of pus
Bleeding on probing
时间窗: 6 months
Presence or absence of bleeding indicated as '1' or '0', respectively
Plaque index
时间窗: 6 months
Presence or absence of plaque indicated as '1' or '0', respectively.
Crestal bone loss
时间窗: 6 months
Measurement of consecutive millimeter markings of the alveolar bone levels
次要结局
- Interleukin-6(6 months)
- Microbiological analysis (Treponema denticola)(6 months)
- HbA1c(6 months)
- Interleukin-1 beta(6 months)
- Microbiological analysis (Porphyromonas gingivalis)(6 months)
研究者
Labban Nawwaf
Department of Prosthetic Dental Sciences, College of Dentistry, King Saud University
King Saud University