Comparative effect of saffron extract with Ibuprofen in dental pain management
Phase 2
- Conditions
- Post-treatment pain after root canal therapy.Diseases of pulp and periapical tissues
- Registration Number
- IRCT2013051713354N1
- Lead Sponsor
- Zahedan University of Medical Sciences, Vice-chancellor for research
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
1-vital teeth with one root canal; 2- moderate to severe pain; 3-patients over 18 years old; 4- patients with at least high school education.
Exclusion criteria: 1- teeth with periapical lesions based on radiographic; 2- patients with history of allergy to saffron; 3- patients with history of allergy to NSAID; 4- diabetes mellitus, cardiovascular disorders, kidney and liver diseases, blood and hormonal disorders and electrolyte imbalance; 5- use of analgesics or opioids during 4 hours before treatment; 6- women in pregnancy or breast feeding period.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pain intensity. Timepoint: 0 - 6 - 12 - 24 and 48 hours after root canal treatment. Method of measurement: Visual Analog Scale (VAS).
- Secondary Outcome Measures
Name Time Method ack of pain intensity. Timepoint: 0-6-12-24-48. Method of measurement: Visual Analog Scale(VAS).