Simultaneous Implant Placement With Vertical and Horizontal Bone Augmentation

Not Applicable

Active, not recruiting

• Conditions: Dental Implant Failed; Alveolar Bone Loss
• Interventions: Procedure: implant placement Simultaneously with ridge augmentation; Procedure: implant placement 6 months after ridge augmentation

• Registration Number: NCT06313229
• Lead Sponsor: Kafrelsheikh University

Brief Summary

The purpose of this study was to report the clinical and radiographical outcomes of using autogenous cortical bone plates combined with sticky allogenic bone graft for augmenting maxillary anterior atrophic combined horizontal and vertical ridge defects with simultaneous versus staged implant placement.

Detailed Description

Sufficient alveolar ridge is a prerequisite for successful implant stability, atrophic ridges defects make the placement of regular implants challenging. A variety of materials and surgical techniques are available for bone augmentation procedures prior implant placement. The present study evaluated the effect of sticky allogenic bone graft for the horizontal and vertical ridge augmentation with simultaneous implant placement using autogenous cortical bone plates in maxillary anterior atrophic ridge defects.

Forty-two patients, with severe maxillary anterior horizontal and vertical atrophic ridge deficiencies were randomly assigned to two groups: staged approach group and simultaneous implant placement group. The two groups were grafted using bone plated buccally and palatally and the defect between plates was grafted by sticky allogenic bone graft. Radiographic examination was performed immediately before bone grafting procedure and at 6, 12 months postoperatively, to evaluate the change of bone width and height.

Study Timeline

• Study First Submitted: 2024-03-09
• Study First Submitted QC: 2024-03-09
• Study Start: 2024-03-13
• Study First Posted: 2024-03-15
• Status Verified: 2025-04
• Last Update Submitted: 2025-04-19
• Last Update Posted: 2025-04-22
• Primary Completion: 2025-04-30
• Study Completion: 2025-05-18

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 42

Inclusion Criteria

• Good general health at the time of surgery
• At least 3 months of healing after tooth extraction
• Horizontally and vertical compromised alveolar ridges

Exclusion Criteria

• Thick cortex in the labial/buccal with less cancellous bone inside;
• Obvious undercut on the labial/buccal side
• Uncontrolled periodontal conditions or other oral disorders;
• history of radiotherapy in the head and neck region

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Simultaneous implant placement approach	implant placement Simultaneously with ridge augmentation	the bone defect was grafted using bone plates buccally and palatally and the defect between plates was grafted by sticky allogenic bone graft combined with simultaneous implant placement.
Staged implant placement approach	implant placement 6 months after ridge augmentation	the bone defect was grafted using bone plates buccally and palatally and the defect between plates was grafted by sticky allogenic bone graft. 6 months later the implant was placed in the grafted site.

Primary Outcome Measures

Name	Time	Method
Stability Quotient of Implants (SQI)	12-month.	The implant stability was recorded using Osstell TM. Following implant insertion, SQI readings were taken immediately, then again after six and twelve months.
Horizontal bone dimensions (HBDs)	12-month.	The HBD alterations were assessed by measuring horizontal spacing between the external edges of labial and palatal bony plates at a level 2mm apical of the fixture platform.
Peri-implant Bone Density (PBD)	12-month.	For consistent measurement of the PBD, 1-mm-diameter Region of interest (RI) was selected and traced 1.2 mm distant from the fixture on the cross-sectional slices followed by counting the threshold pixels inside the RI.

Trial Locations

Locations (1)

faculty of dentistry, kafrelsheikh University; 🇪🇬 Kafr Ash Shaykh, Kafrelsheikh, Egypt