Hereditary Thrombophilia in the Pathogenesis of Myocardial Infarction and Coronary Artery Bypass Graft Occlusion: New Role for an Old Actress.
Completed
- Conditions
- Heart attack10011082acute coronary syndrome
- Registration Number
- NL-OMON42575
- Lead Sponsor
- Sint Antonius Ziekenhuis
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 887
Inclusion Criteria
Patients with unstable angina or non-ST-segment elevation myocardial infarction.
Age above 18 years;ST-segment elevation myocardial infarction (STEMI) patients for comparison will be selected from an existing dataset of ongoing trial (i.e., POPular Genetics).
Exclusion Criteria
Patients who are unable or unwilling to give informed consent (e.g., due to metal illnesses or inability to understand Dutch language).
Individuals younger than 18 years of age.
Patients with previous ST-segment elevation myocardial infarction (STEMI)
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Prevalence of factor V Leiden or Prothrombin G20210A in STEMI as compared to<br /><br>NSTEMI/uAP patients.</p><br>
- Secondary Outcome Measures
Name Time Method <p>Hemorrhagic complications during the index hospitalization in patients with<br /><br>versus without factor V Leiden or prothrombin G20210A mutations.</p><br>