MedPath

Initial Stay Times and Heat Mitigation Controls for Uncompensable Occupational Heat Stress - Part II

Not Applicable
Not yet recruiting
Conditions
Core Temperature
Heat Stress, Exertional
Heat Fatigue
Exercise
Interventions
Other: Simulated work in the heat
Registration Number
NCT06543719
Lead Sponsor
University of Ottawa
Brief Summary

Workplaces rely on upper heat stress limits provided by the American Conference of Governmental Industrial Hygienists (ACGIH) to manage the health and safety of workers in hot environments. This is primarily achieved by interspersing work with rest periods, the length of which is dictated by environmental conditions and work intensity, to maintain core temperature at or below 38.0°C (equivalent to a 1°C increase in body core temperature above resting levels). However, these guidelines employ a "one size fits all" approach to exposure limits that does not consider individual variation (e.g., age) between workers. Moreover, they fail to provide direction on the safe, initial stay times before these heat-mitigation controls should be employed (i.e., rest breaks) in conditions exceeding upper heat stress limits. While recent work has generated estimates of the initial stay times for young to older men before heat-mitigation controls are required for moderate-intensity work, information on initial stay times for heavy-intensity work remains to be assessed. This project will assess the initial stay times for heavy-intensity work for a single work bout as well as for a second work bout that is preceded by an extended rest period such as a lunch break and a work bout performed on the next day to determine if refinements in initial stay times across these periods may be required. Further, the investigators will evaluate if the application of recommended work-rest allocations thereafter would alleviate increases in core temperature for the duration of the work period (e.g., start of shift versus post-lunch period). Given the known age-differences in heat loss that can modulate core temperature regulation during an exercise-heat stress, the investigators will assess responses response in young and older adults.

Detailed Description

Not available

Recruitment & Eligibility

Status
NOT_YET_RECRUITING
Sex
Male
Target Recruitment
20
Inclusion Criteria
  • young (18-30 years) and older adults (50-69 years)
  • habitually active, not endurance trained (<2 sessions per week, <150 minutes per week)
  • non-smoking
  • English or French speaking
  • ability to provide informed consent
Exclusion Criteria
  • pre-existing health conditions (e.g., diabetes, hypertension)
  • use of medication deemed to significantly modulate thermoregulatory function and heat tolerance (e.g., antidepressants, antihistamines, diuretics)
  • engaged in jobs and/or activities that involve frequent exposure to hot environments (e.g., regular sauna use)

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Older adults. Adults aged 50-69 with no pre-existing health conditionsSimulated work in the heatAdults aged 50-69 with no pre-existing health conditions
Younger adults.Simulated work in the heatAdults aged 18-30 years with no pre-existing health conditions
Primary Outcome Measures
NameTimeMethod
Average core temperaturePeriod of work-rest allocations following initial stay time for morning of day 2

Average core temperature following initial stay time

Initial stay timeEnd of third (morning day 2) continuous work bout

Total continuous work time to achieve an initial absolute increase in core temperature of 38°C (equivalent to a 1°C increase in body core temperature above resting levels) (note: in instances where a participant voluntarily terminates work prematurely before the absolute core temperature of ≥38°C (or relative increase of ≥1°C) is achieved or the absolute core temperature is \<38°C (or relative increase of \<1°C), the time of termination or end of the work bout will be taken as the initial stay time respectively).

Secondary Outcome Measures
NameTimeMethod
Systolic blood pressureEnd of third (morning day 2) work period

Arterial blood pressure measured via automated oscillometry

Skin temperature at initial stay timeEnd of first (morning day 2) continuous work bout

Skin temperature (4 sites) measured at the initial increase in absolute core temperature of 38°C (or relative increase of 1°C)

Average skin temperaturePeriod of work-rest allocations following initial stay time for morning of day 2

Average heart rate following initial stay time

Mean arterial pressureEnd of third (morning day 2) work period

Calculated as 1/3 \* systolic blood pressure + 2/3 \* diastolic blood pressure

Rating of Perceived ExertionPeriod of work-rest allocations following initial stay time for morning of day 2

Perceived exertion assessed via a self-report questionnaire upon verbal prompting (6: no exertion at all to 20: maximal exertion).

Heart rate at initial stay timeEnd of first (morning day 2) continuous work bout

Heart rate at the initial increase in absolute core temperature of 38°C (or relative increase of 1°C)

Rate pressure productEnd of third (morning day 2) work period

Calculated as systolic blood pressure \* heart rate

Average heart ratePeriod of work-rest allocations following initial stay time for morning of day 2

Average heart rate following initial stay time

Diastolic blood pressureEnd of third (morning day 1) work period

Arterial blood pressure measured via automated oscillometry

Change in plasma volumeEnd of third (morning day 2) work period

Determined from venous blood samples

Fluid consumptionEnd of third (morning day 2) work period

Cumulative fluid consumption calculated by weighing the participant's water intake

Fluid lossEnd of third (morning day 2) work period

Fluid loss calculated as the change in body mass (corrected for food/fluid consumption).

Thermal comfort scalePeriod of work-rest allocations following initial stay time for morning of day 2

Thermal comfort assessed via a visual analog scale ("How comfortable does your body temperature feel?") (4: very uncomfortable to 1: comfortable)

Thirst sensation scalePeriod of work-rest allocations following initial stay time for morning of day 2

Assessed via a visual analog scale ("How thirsty are you?") (9: very, very thirsty to 1: Not thirsty at all)

Orthostatic Intolerance Symptoms AssessmentEnd of third (afternoon day 1) continuous work bout

Cumulative sum of scores on 6 questions asking participant to rank symptoms associated with orthostatic intolerance. All symptoms scored on a scale from 0 (none) to 10 (worst possible) and include feelings of: (1) "dizziness, lightheadedness, feeling faint, or feeling like you might black out"; (2) "Problems with vision (blurring, seeing spots, tunnel vision, etc.)"; (3) "Weakness"; (4) "Fatigue"; (5) "Trouble concentrating"; and (6) "Head and neck discomfort"

Trial Locations

Locations (1)

University of Ottawa

🇨🇦

Ottawa, Ontario, Canada

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