Case Notes Review on Patients With Hereditary Haemorrhagic Telangiectasia

Recruiting

• Conditions: Telangiectasia, Hereditary Hemorrhagic

• Registration Number: NCT00230685
• Lead Sponsor: Imperial College London

Brief Summary

This observational study is for individuals with Hereditary haemorrhagic telangiectasia and pulmonary arteriovenous malformations that are reviewed at the Hammersmith Hospital, London.

Detailed Description

The Hammersmith Hospital provides a clinical service for patients with Hereditary haemorrhagic telangiectasia and pulmonary arteriovenous malformations that is unique in the United Kingdom. Measurements obtained as part of standard clinical practice that has evolved since 1985 allow us to assess whether particular groups of individuals that we see are more prone to recognised complications such as strokes, brain abscesses, pregnancy related complications or pulmonary hypertension. We hypothesise that certain clinical characteristics will predict the susceptibility of individuals to particular complications.

Study Timeline

• Study Start: 2000-01
• Study First Submitted: 2005-09-29
• Study First Submitted QC: 2005-09-29
• Study First Posted: 2005-10-03
• Status Verified: 2023-09
• Last Update Submitted: 2023-09-25
• Last Update Posted: 2023-09-28
• Primary Completion: 2028-01
• Study Completion: 2028-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 2000

Inclusion Criteria

• Patients attending Hammersmith Hospital

Exclusion Criteria

• None

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Venous thromboemboli (VTE)	Prospective	VTE of any origin
Stroke	Prospective	Ischaemic stroke attributable to PAVMs

Trial Locations

Locations (1)

Respiratory Medicine, Hammersmith Hospital; 🇬🇧 London, United Kingdom