Factors and Prognosis of Obstructive Pyelonephritis Patients

Recruiting

Brief Summary: Acute obstructive pyelonephritis is a condition with a high risk of complications and may require admission to the intensive care unit.

Most of the available data on this condition comes from small, retrospective, single-centre series.

To date, no large-scale study has examined the factors associated with the prognosis of patients admitted to intensive care for acute obstructive pyelonephritis.

The aim of this study is to describe the population and prognosis of patients admitted to the intensive care unit for the management of acute obstructive pyelonephritis, and to identify factors associated with a poor prognosis in these patients.

Detailed Description: The retrospective and multicenter study consists of a retrospective and pseudonymous collection of data from medical reports of patients treated, over the period 2015-2022, in each intensive care unit agreeing to participate, .

Investigators from each participating center will be responsible for screening on all hospitalized patients over the period 2015-2022. Patients who have been hospitalized for the management of acute obstructive pyelonephritis will be included, in the absence of non-inclusion criteria.

Recruitment & Eligibility

Inclusion Criteria

Patients over 18 years of age
Hospitalized in intensive care for management of acute obstructive pyelonephritis
Patients affiliated to a Social Security System

Exclusion Criteria

Primary Outcome Measures

Name	Time	Method
The primary endpoint will be a combined endpoint of death, and/or stage 3 AKI ( KDIGO classification), and/or non-recovery of renal function.	up to 30 days after admission to intensive care

Secondary Outcome Measures

Name	Time	Method
the incidence of acute renal failure defined by KDIGO 2 and 3	up to 30 days after admission to intensive care
the incidence of Renal replacement therapy	up to 30 days after admission to intensive care
The number of days alive without Renal replacement therapy	up to 30 days after admission to intensive care
the incidence of non-recovery of renal fuction	up to 30 days after admission to intensive care
The number of days alive without antibiotics	up to 30 days after admission to intensive care
Death	up to 30 days after admission to intensive care
Stage 3 Acute kidney injury (KDIGO classification)	up to 30 days after admission to intensive care
failure to recover renal function	up to 30 days after admission to intensive care .	defined as creatinine levels greater than 150% of baseline value
the incidence of acute renal failure defined by KDIGO 1	up to 30 days after admission to intensive care
The number of days alive without catecholamines	up to 30 days after admission to intensive care
The number of days alive without	up to 30 days after admission to intensive care
Death rate	up to 30 days after admission to intensive care

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