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Traditional Versus ScvO2 Guided Perioperative Fluid Therapy

Phase 4
Completed
Conditions
Perioperative Care
Interventions
Procedure: Intravenous fluid
Registration Number
NCT00468793
Lead Sponsor
Haukeland University Hospital
Brief Summary

Perioperative goal directed fluid therapy by means of an esophageal doppler has been shown to reduce morbidity and length of stay. In this study patients undergoing elective bowel surgery will be randomised to traditional fluid therapy with crystalloids versus fluid boluses guided by central venous oxygen saturation. The primary outcome will be complications after surgery.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
240
Inclusion Criteria
  • Elective bowel surgery,
  • Able to give informed consent
Exclusion Criteria
  • Coagulation defect,
  • Renal failure,
  • Valvular stenosis

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
2Intravenous fluidFluid therapy guided by blood pressure and urine production
1Intravenous fluidScvO2 guided fluid therapy
Primary Outcome Measures
NameTimeMethod
Postoperative morbiditypostoperative day 30
Secondary Outcome Measures
NameTimeMethod
serum creatininepostoperative day 3

Trial Locations

Locations (1)

Haukeland University Hospital

🇳🇴

Bergen, Norway

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