To compare two drugs hyperbaric levobupivacaine and hyperbaric bupivacaine for cesarean section

Phase 2/3

Not yet recruiting

• Conditions: Medical and Surgical,

• Registration Number: CTRI/2023/06/053720
• Lead Sponsor: Dr Reena makhni

Brief Summary

Regional anaesthesia for caesarean section has several advantages over general anaesthesia as it minimise side effects and complications as well as there is less interference with normal metabolic processes and vital functions.

The present study will be conducted in department of anesthesiology and intensive care government medical college amritsar after approval from the institutinal thesis and ethics committee.the primary objective of this study will be to assess the onset and duration of sensory and motor blockade and also any haemodynamic changes associated with use of study drugs.

Detailed Description

Not available

Study Timeline

• Study Start: 2023-06-19
• Last Update Posted: 2023-08-06

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: Female
• Target Recruitment: 60

Inclusion Criteria

Age group between 18-40years of female sex,ASA grade 2 pregnant patients at term undergoing caesarean section with normal neurological status and cooperative patients.

Exclusion Criteria

Patients refusal for written consent for spinal anaesthesia,any neurological disorder,any coagulation disorder, allergy to study drug, history of any coexisting diseases like IHD,impaired renal functions, rheumatoid arthritis,severe liver disease and also contraindications to regional anaesthesia.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Hemodynamic changes	Onset & duration of sensory and motor blockade for 6 hours post op and haemodynamic parameters for 24 hrs. | Hemodynamic changes
Onset & duration of sensory and motor blockade	Onset & duration of sensory and motor blockade for 6 hours post op and haemodynamic parameters for 24 hrs. | Hemodynamic changes

Secondary Outcome Measures

Name	Time	Method
Adverse effects like nausea, vomiting, pruritis, shivering, sedation.	To assess the quality of intramuscular muscle relaxation.

Trial Locations

Locations (1)

Government medical college; 🇮🇳 Amritsar, PUNJAB, India

Government medical college

🇮🇳Amritsar, PUNJAB, India

Dr Bommakanti Nandini

Principal investigator

8309873495

nandinidevi.100@gmail.com